1,2-Benzisothiazol-3(2H)-one, 2-methyl-, 1,1-dioxide
N-METHYLSACCHARIN
CAS: 15448-99-4
Molecular Formula: C8H7NO3S
1,2-Benzisothiazol-3(2H)-one, 2-methyl-, 1,1-dioxide - Names and Identifiers
1,2-Benzisothiazol-3(2H)-one, 2-methyl-, 1,1-dioxide - Physico-chemical Properties
| Molecular Formula | C8H7NO3S |
| Molar Mass | 197.21 |
| Density | 1.486±0.06 g/cm3(Predicted) |
| Melting Point | 131 °C |
| Boling Point | 366.3±25.0 °C(Predicted) |
| pKa | -12.83±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| MDL | MFCD00059263 |
1,2-Benzisothiazol-3(2H)-one, 2-methyl-, 1,1-dioxide - Upstream Downstream Industry
1,2-Benzisothiazol-3(2H)-one, 2-methyl-, 1,1-dioxide - Introduction
N-METHYLSACCHARIN(N-METHYLSACCHARIN) is a common artificial sweetener. Its chemical name is N-methyl -2-saccharin, chemical formula is C8H9NO3S, its molecular structure has a methyl substituted on the nitrogen atom of saccharin. The N-METHYLSACCHARIN is white crystal, taste sweet without aroma.
The primary use of N-METHYLSACCHARIN is as a sweetener for foods and beverages. It is sweeter than sucrose, but it has almost no calories and does not cause tooth decay. Therefore, it is often used to make low-calorie and sugar-free foods. N-METHYLSACCHARIN can also be used in the pharmaceutical industry as a pharmaceutical or cosmetic sweetener.
A common method of preparing N-METHYLSACCHARIN is through the methylation reaction of saccharin. This reaction transfers the methyl group in the methanol to the nitrogen atom of the saccharin. The preparation process requires a methylating agent, usually sodium formate and a sulfuric acid catalyst. The reaction is generally carried out at elevated temperature and purified by crystallization to give the pure product.
Regarding safety information, N-METHYLSACCHARIN has been approved by the FDA as a food additive and is considered safe in many countries. It has a strong sweet taste and requires less, but long-term consumption of excessive amounts may have negative health effects. Some studies suggest that large doses of N-METHYLSACCHARIN may be associated with the development of cancer. Therefore, it is recommended to follow appropriate dosage and frequency of consumption when using N-METHYLSACCHARIN, and to follow food safety guidelines. For pregnant women, children and people allergic to sweeteners, should try to avoid the use.
The primary use of N-METHYLSACCHARIN is as a sweetener for foods and beverages. It is sweeter than sucrose, but it has almost no calories and does not cause tooth decay. Therefore, it is often used to make low-calorie and sugar-free foods. N-METHYLSACCHARIN can also be used in the pharmaceutical industry as a pharmaceutical or cosmetic sweetener.
A common method of preparing N-METHYLSACCHARIN is through the methylation reaction of saccharin. This reaction transfers the methyl group in the methanol to the nitrogen atom of the saccharin. The preparation process requires a methylating agent, usually sodium formate and a sulfuric acid catalyst. The reaction is generally carried out at elevated temperature and purified by crystallization to give the pure product.
Regarding safety information, N-METHYLSACCHARIN has been approved by the FDA as a food additive and is considered safe in many countries. It has a strong sweet taste and requires less, but long-term consumption of excessive amounts may have negative health effects. Some studies suggest that large doses of N-METHYLSACCHARIN may be associated with the development of cancer. Therefore, it is recommended to follow appropriate dosage and frequency of consumption when using N-METHYLSACCHARIN, and to follow food safety guidelines. For pregnant women, children and people allergic to sweeteners, should try to avoid the use.
Last Update：2024-04-09 02:00:50
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CAS: 15448-99-4
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Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
CAS: 15448-99-4
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: N-Methylsaccharin Visit Supplier Webpage Request for quotation
CAS: 15448-99-4
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CAS: 15448-99-4
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View History
Raw Materials for 1,2-Benzisothiazol-3(2H)-one, 2-methyl-, 1,1-dioxide
Benzenecarboximidic acid, N-methyl- (9CI)
N-HYDROXYMETHYLSACCHARIN
2-Methyl-1,2-benzothiazol-3(2H)-one
Piroxicam
4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide
Methanol
Dimethyl sulfate
N-HYDROXYMETHYLSACCHARIN
2-Methyl-1,2-benzothiazol-3(2H)-one
Piroxicam
4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide
Methanol
Dimethyl sulfate